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In hormone replacement therapy, it seriously matters which delivery method is used and the dosage administered. To that point, pellet implant therapy is widely accepted as the most effective and safest form of HRT available. The subcutaneous pellet implant is, in fact, one of the oldest and most researched hormone delivery methods in use.1 This approach to HRT most closely simulates the body’s own hormone delivery method in that it circulates physiologic amounts of hormone in the bloodstream around-the-clock. And it lasts for months at a time. Pellets can also respond to the body when it needs more hormone, for instance during exercise or stressful situations. Research shows that pills, patches and other common delivery methods simply cannot provide the same desirable steady dose that pellets can.2 Importantly, it’s this stable supply of low dose hormones that’s required to support homeostasis (internal equilibrium) and good health.
All that being said, many practitioners do not fully understand how to achieve hormonal balance using this method. It is not a one size fits all solution, nor is it a hit and miss proposition. Precision dosing and careful monitoring are imperative to avoiding the side effects or adverse reactions from hormone levels that are too high. Like any medication you take, the dosage determines the outcome. Too much or too little can sometimes result in serious health issues. When you read of patients having problems with pellets, it’s generally attributable to physicians who are not correctly dosing them.

The SottoPelle® Difference

If you are already on or thinking about trying SottoPelle® bioidentical pellet implant therapy, here are some facts you need to know about why our method is different from others.

1. Our treatment is science-based and has a proven track record. The pellet method of delivering hormones has been in use and studied since the 1940s.3 It’s shown to be the safest and most effective method available. Abundant scientific literature dating back decades likewise supports the use of bioidentical hormones versus pharmaceutical synthetics. When properly administered, these human-identical hormones can provide relief from menopausal symptoms in addition to many health benefits.4,5

2. After years of personal research and evaluation, our founder, Dr. Gino Tutera developed a uniquely precise bioidentical pellet implant system that includes:

• Proper testing and diagnosis of hormone deficiency;
• A proprietary algorithmic-based dosing software that provides customized treatment appropriate to each individual patient;
• A unique implantation method that helps prevent extrusion of pellets;
• Proper follow-up and monitoring of hormone levels (including thyroid), blood lipids, and other indicators of health.

Of course, the most crucial factor in providing SottoPelle® patients with a unique and beneficial BHRT experience is the expertise of our highly trained physicians and the partnership they create with each patient. By precisely adhering to our unique system and establishing open communication with patients, our physicians can help them regain the quality of life they once had. That’s what hormonal balance is all about.

SottoPelle® BHRT Pellet Experts

SottoPelle® has specialized in BHRT using the pellet method longer than most. Our founder, Dr. Gino Tutera, developed the proprietary method that makes us a leader in our field. We have a long history of success when it comes to balancing hormones and helping people take control of their health. In fact, we are honored to say that, according to Ranking Arizona, an annual consumer publication by AZ Big Media, our patients have voted us Arizona’s #1 Hormone Therapy Clinic in 2015.

Call Us Today!

Learn more about SottoPelle® at www.sottopelletherapy.com and then give us a call at (877) 473-5538 to schedule a consultation.


1Greenblatt R. Indications for hormone pellets in the therapy of endocrine and gynaecological disorders. Am J Obstet-Gynecol 1949; 57:294-301. http://www.ajog.org/article/0002-9378(49)90429-9/abstract
2 Smith RN, Studd JW. Recent advances in hormone replacement therapy. (Review) Brit Jour Hosp Med, 1993, 49(11) 799-808. https://www.ncbi.nlm.nih.gov/pubmed/8334484
3 Cardozo L, Gibb D, Tuck S, et al. The effects of subcutaneous hormone implants during the climacteric. Maturitas 1984;5:177-184. http://www.htcapractitioner.com/wordpress/wp-content/uploads/2015/07/Cardozo-84-The-effects-of-subcutaneous-hormone-implants-during-the-climacteric.pdf
4 Schwartz E, Holtorf K. Hormones in wellness and disease prevention: common practices, current state of the evidence, and questions for the future. Prim Care Clin Office Pract 2008; 35 (4): 669–705. http://www.holtorfmed.com/pdf/04-Hormones-in-Wellness.pdf
5 Moskowitz D. A comprehensive review of the safety and efficacy of bioidentical hormones for the management of menopause and related health risks. Altern Med Rev. 2006 Sep;11(3):208-23. https://www.ncbi.nlm.nih.gov/pubmed/17217322