Testosterone, Andropause and Men’s Health
A man’s testosterone (T) is his most vital hormone. It impacts everything from muscles, brain and sex drive, to blood, arteries, organs and glands. Take it away and his well-being goes with it. That’s why low testosterone (Low T) can be so devastating.
Andropause: Every man begins a gradual drop in hormone production around age 30. He loses approximately one to two percent a year until sometime between 40 and 50 years of age, his T levels fall sharply and signify the beginning of andropause. By age 50, most men have lost over half of their T, which can have a major impact on their health. Lifestyle changes alone aren’t sufficient to address hormonal imbalances. Therefore, it’s important for men to be aware of early symptoms and start checking their hormone levels in their 40’s with a simple blood panel – before Low T strikes.
Symptoms: Fatigue, mood swings, poor mental focus, low stamina, sleep disturbances, memory loss, depression, erectile dysfunction, irritability, decreased sex drive, anxiety, bone loss, high cholesterol, loss of muscle mass, weight gain, belly fat, and decreased sense of well-being. Studies show a link between Low T and cardiovascular risk, insulin resistance, high cholesterol and osteoporosis.
Health Benefits: Enhances energy, well-being, memory, concentration, lean body mass, muscle strength, bone density, metabolism and sexual function. Relieves depression, anxiety and fatigue. Helps maintain a healthy supply of red blood cells, cardiovascular function and a normal lipid profile.
Testosterone Replacement Therapy (TRT): There are many different forms of TRT and it’s important to distinguish between the synthetic type found in most traditional hormone replacement therapies (HRT) and natural, plant-based compounds used in bio-identical hormone replacement therapy (BHRT). Synthetic pills, patches, gels, drops, troches, creams and injections with generic doses often contain harmful chemicals and additives that can pose serious health risks. BHRT uses natural hormones whose molecular structure contains the exact biochemical structure as the human hormone, with no side effects.
The Power of Pellets®: Delivery is key to effective TRT. Studies show that hormone pellets – about the size of a grain of rice and slipped under the skin – provide the most effective delivery system because they are monitored naturally by the body’s own heart rate for 24-7 distribution exactly when needed. This approach can restore the body to its normal physiology. Pellets last on average 5 – 6 months for men.
Dosing: Pellets work best when they are precisely dosed and individualized for each patient’s specific needs. Safe and effective TRT involves: accurate testing and analysis; bioidentical hormones, proper dosage and round the clock delivery to sustain hormone levels. Restoring T to normal, physiologic levels. means customizing the dosage to the individual and monitoring patients on a regular basis.
Beyond Andropause: Parkinson’s & Traumatic Brain Injury: A number of retired NFL players have turned to SottoPelle® for relief from a variety of issues related to brain injuries. New studies show that Low T is related to neurodegenerative conditions such as Traumatic Brain Injury (TBI), concussions, Parkinson’s disease (PD), Alzheimer’s and dementia. Since the sex hormones are also closely related to cognitive and neuromuscular function, positive results are being reported in patients with PD, TBI and PTSD.
SottoPelle® has been diagnosing andropause and treating men with Low T for over 20 years. With founder, Gino Tutera MD, being the inventor of the patented BioCalc® method of pellet dosing, SottoPelle® remains the BHRT global leader. We understand the strain that Low T can put on a man’s energy, drive and quality of life and that your body needs a steady flow of testosterone that it may not always be able to produce by itself. We use only the purest pellets and quality plant-based compounds to deliver the right amount of testosterone your body requires exactly when it needs it. This can keep you going and feeling great! Reclaim your life with SottoPelle® — helping people live longer, stronger and healthier!
Cattabiani C, Basaria S, Ceda GP, et al. Relationship between Testosterone deficiency and Cardiovascular risk and Mortality in Adult Men. J Endocrinol Invest. 2011 Nov 8; [PubMed]
Leung-Wing Chu, Sidney Tam, Rachel LC Wong, Ping-Yiu Yik, Youqiang Song, Bernard MY Cheung, John E Morley, Karen SL Lam. Bioavailable testosterone predicts a lower risk of Alzheimer’s Disease in older men. Journal of Alzheimer’s Disease 2010; 21 (4).
- Srinivas-Shankar U, Roberts SA, Connolly MJ, et al. Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind, placebo-controlled study. J Clin Endocrinol Metab. 2010;95:639–50. [PubMed]
Farid Saad,1,* Antonio Aversa,2 Andrea M Isidori,2 and Louis J Gooren3. Testosterone as Potential Effective Therapy in Treatment of Obesity in Men with Testosterone Deficiency: A Review. Curr Diabetes Rev. Mar 2012; 8(2): 131-143.
Moffat SD, Zonderman AB,Metter EJ,Blackman MR,Harman SM, Resnick SM. Longitudinal assessment of serum free testosterone concentration predicts memory performance and cognitive status in elderly men. J Clin Endocrinol Metab. 2002 Nov;87(11):5001-7.
Gino Tutera and R. Don Gambrell Jr. Marked reduction of breast, endometrial and ovarian cancer in users of bio-identical estradiol and testosterone subcutaneous pellets, Maturitas, 2009. Journal of Spanish Society of Anti-Aging Medicine and Longevity, Vol. 18, Sept. 2014, pp 27-33.
- Travison TG, Araujo AB, Kupelian V, O’Donnell AB, McKinlay JB. The relative contributions of aging, health, and lifestyle factors to serum testosterone decline in men. J Clin Endocrinol Metab. 2007;92:549
- Kapoor D, Goodwin E, Channer KS, Jones TH. Testosterone replacement therapy improves insulin resistance, glycaemic control, visceral adiposity and hypercholesterolaemia in hypogonadal men with type 2 diabetes. Eur J Endocrinol. 2006;154:899–906. [PubMed]
- Kenny AM, Fabregas G, Song C, Biskup B, Bellantonio S. Effects of testosterone on behavior, depression, and cognitive function in older men with mild cognitive loss. J Gerontol A Biol Sci Med Sci. 2004;59:75–8. [PubMed]
- Marin P, Holmang S, Jonsson L, et al. The effects of testosterone treatment on body composition and metabolism in middle-aged obese men. Int J Obes Relat Metab Disord. 1992;16:991–7. [PubMed]
Seidel B, Lewis T, Kucer B. The decision to provide testosterone supplementation in patients with traumatic brain injury. PM R. 2013 Nov;5(11):985-6.
Young TP, Hoaglin HM, Burke DT. The role of serum testosterone and TBI in the in-patient rehabilitation setting. Brain Inj. 2007 Jun;21(6):645-9.
- Emmelot-Vonk MH, Verhaar HJ, Nakhai Pour HR, et al. Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. Jama. 2008;299:39–52. [PubMed]
Holland J, Bandelow S, Hogervorst E. Testosterone levels and cognition in elderly men: a review. Maturitas. 2011 Aug;69(4):322-37.